Hiccups due to gastroesophageal reflux

Lt Lee R. Schreiber, Michael R. Bowen, Frank A. Mino, Timothy Craig

Research output: Contribution to journalArticlepeer-review

15 Scopus citations


Hiccups (singultus) are most often a transient phenomenon that resolves without medical therapy. Intractable hiccups can be an indication of a serious underlying disease process and should be investigated. To demonstrate the evaluation of intractable singultus, we describe a patient who had unsuccessful outpatient therapy for persistent hiccups and who was subsequently found to have gastroesophageal reflux (GER). Efforts to determine the cause of the hiccups were negative except for endoscopically proven GER. On follow-up visits, antisingultus medications were withdrawn without return of hiccups, and repeat endoscopy showed substantial healing of the esophagitis. We conclude that GER may be underestimated as a cause of hiccups.

Original languageEnglish (US)
Pages (from-to)217-219
Number of pages3
JournalSouthern Medical Journal
Issue number2
StatePublished - Feb 1995

All Science Journal Classification (ASJC) codes

  • Medicine(all)


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