High Performance Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Detection for Capillary Electrophoresis

Steven A. Hofstadler; Joanne C. Severs; Richard D. Smith; Frank D. Swanek; Andrew G. Ewing

doi:10.1002/jhrc.1240191105

High Performance Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Detection for Capillary Electrophoresis

Steven A. Hofstadler, Joanne C. Severs, Richard D. Smith, Frank D. Swanek, Andrew G. Ewing

Chemistry

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

We describe the current state of the on-line combination of capillary electrophoresis (CE) electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS), and discuss aspects of the FTICR technique relevant to its use as a detection scheme for on-line separations. Aspects including sensitivity, mass resolution, duty cycle, and tandem mass spectrometric capabilities are discussed in the context of online separations with examples from the authors' laboratory.

Original language	English (US)
Pages (from-to)	617-621
Number of pages	5
Journal	HRC Journal of High Resolution Chromatography
Volume	19
Issue number	11
DOIs	https://doi.org/10.1002/jhrc.1240191105
State	Published - Nov 1996

All Science Journal Classification (ASJC) codes

Chemical Engineering(all)

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10.1002/jhrc.1240191105

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abstract = "We describe the current state of the on-line combination of capillary electrophoresis (CE) electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS), and discuss aspects of the FTICR technique relevant to its use as a detection scheme for on-line separations. Aspects including sensitivity, mass resolution, duty cycle, and tandem mass spectrometric capabilities are discussed in the context of online separations with examples from the authors' laboratory.",

author = "Hofstadler, {Steven A.} and Severs, {Joanne C.} and Smith, {Richard D.} and Swanek, {Frank D.} and Ewing, {Andrew G.}",

year = "1996",

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AU - Hofstadler, Steven A.

AU - Severs, Joanne C.

AU - Smith, Richard D.

AU - Swanek, Frank D.

AU - Ewing, Andrew G.

PY - 1996/11

Y1 - 1996/11

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AB - We describe the current state of the on-line combination of capillary electrophoresis (CE) electrospray ionization (ESI) Fourier transform ion cyclotron resonance (FTICR) mass spectrometry (MS), and discuss aspects of the FTICR technique relevant to its use as a detection scheme for on-line separations. Aspects including sensitivity, mass resolution, duty cycle, and tandem mass spectrometric capabilities are discussed in the context of online separations with examples from the authors' laboratory.

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High Performance Fourier Transform Ion Cyclotron Resonance Mass Spectrometric Detection for Capillary Electrophoresis

Abstract

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