Abstract
A plurality of articles discussing combined effects of acoustic high-pressure and heat caused by acoustic vibration on biological tissues and cells has been introduced. Herein, we contribute the first article describing the use of a blunt impact caused by high-power ultrasonic pulses for insulting living human skin cells, wherein the impact does not generate heat. The pulses were generated by an apparatus comprising a liquid horn (i.e., water filled horn) including a concave transducer, an apparatus comprising a solid horn (i.e., aluminum waveguide horn) including a disc transducer, and a laser induced ultrasonic shock wave system, wherein the pressures caused by the pulses were measured by a hydrophone, and wherein temperature was monitored by thermocouples. Phenomena indicating cellular insult and injury (e.g., shrinkage or lift-off) were clearly visualized with scanning acoustic microscopy with frequency at 1.0 GHz.
| Original language | English (US) |
|---|---|
| Pages (from-to) | 1273-1276 |
| Number of pages | 4 |
| Journal | Proceedings of the IEEE Ultrasonics Symposium |
| Volume | 2 |
| State | Published - 2001 |
| Event | 2001 Ultrasonics Symposium - Atlanta, GA, United States Duration: Oct 6 2001 → Oct 10 2001 |
All Science Journal Classification (ASJC) codes
- Acoustics and Ultrasonics