TY - JOUR
T1 - High sodium intake increases blood pressure and risk of kidney disease. From the Science of Salt
T2 - A regularly updated systematic review of salt and health outcomes (August 2016 to March 2017)
AU - Malta, Daniela
AU - Petersen, Kristina S.
AU - Johnson, Claire
AU - Trieu, Kathy
AU - Rae, Sarah
AU - Jefferson, Katherine
AU - Santos, Joseph Alvin
AU - Wong, Michelle M.Y.
AU - Raj, Thout Sudhir
AU - Webster, Jacqui
AU - Campbell, Norm R.C.
AU - Arcand, Jo Anne
N1 - Publisher Copyright:
©2018 Wiley Periodicals, Inc.
PY - 2018/12
Y1 - 2018/12
N2 - The purpose of this review was to identify, summarize, and critically appraise studies on dietary salt and health outcomes that were published from August 2016 to March 2017. The search strategy was adapted from a previous systematic review on dietary salt and health. Studies that meet standards for methodological quality criteria and eligible health outcomes are reported in detailed critical appraisals. Overall, 47 studies were identified and are summarized in this review. Two studies assessed all-cause or disease-specific mortality outcomes, eight studies assessed morbidity reduction-related outcomes, three studies assessed outcomes related to symptoms/quality of life/functional status, 25 studies assessed blood pressure (BP) outcomes and other clinically relevant surrogate outcomes, and nine studies assessed physiologic surrogate outcomes. Eight of these studies met the criteria for outcomes and methodological quality and underwent detailed critical appraisals and commentary. Five of these studies found adverse effects of salt intake on health outcomes (BP; death due to kidney disease and initiation of dialysis; total kidney volume and composite of kidney function; composite of cardiovascular disease (CVD) events including, and risk of mortality); one study reported the benefits of salt restriction in chronic BP and two studies reported neutral results (BP and risk of CKD). Overall, these articles confirm the negative effects of excessive sodium intake on health outcomes.
AB - The purpose of this review was to identify, summarize, and critically appraise studies on dietary salt and health outcomes that were published from August 2016 to March 2017. The search strategy was adapted from a previous systematic review on dietary salt and health. Studies that meet standards for methodological quality criteria and eligible health outcomes are reported in detailed critical appraisals. Overall, 47 studies were identified and are summarized in this review. Two studies assessed all-cause or disease-specific mortality outcomes, eight studies assessed morbidity reduction-related outcomes, three studies assessed outcomes related to symptoms/quality of life/functional status, 25 studies assessed blood pressure (BP) outcomes and other clinically relevant surrogate outcomes, and nine studies assessed physiologic surrogate outcomes. Eight of these studies met the criteria for outcomes and methodological quality and underwent detailed critical appraisals and commentary. Five of these studies found adverse effects of salt intake on health outcomes (BP; death due to kidney disease and initiation of dialysis; total kidney volume and composite of kidney function; composite of cardiovascular disease (CVD) events including, and risk of mortality); one study reported the benefits of salt restriction in chronic BP and two studies reported neutral results (BP and risk of CKD). Overall, these articles confirm the negative effects of excessive sodium intake on health outcomes.
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U2 - 10.1111/jch.13408
DO - 10.1111/jch.13408
M3 - Article
C2 - 30402970
AN - SCOPUS:85056163084
SN - 1524-6175
VL - 20
SP - 1654
EP - 1665
JO - Journal of Clinical Hypertension
JF - Journal of Clinical Hypertension
IS - 12
ER -