High-throughput screening for drug discovery

James R. Broach; Jeremy Thorner

doi:10.1038/384014a0

High-throughput screening for drug discovery

James R. Broach
, Jeremy Thorner

Research output: Contribution to journal › Review article › peer-review

2 Scopus citations

Abstract

Recent progress in elucidating the mechanisms underlying human disease has dramatically increased the number of protein targets available for potential drug treatment. Concurrently, new approaches have increased the number of compounds that can be tested for activity against these targets. Together, these trends have stimulated the adoption of high-throughput screening as a primary tool for early-stage drug discovery.

Original language	English (US)
Pages (from-to)	14-16
Number of pages	3
Journal	Nature
Volume	384
Issue number	6604 SUPPL.
DOIs	https://doi.org/10.1038/384014a0
State	Published - Nov 7 1996

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

General

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10.1038/384014a0

Cite this

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title = "High-throughput screening for drug discovery",

abstract = "Recent progress in elucidating the mechanisms underlying human disease has dramatically increased the number of protein targets available for potential drug treatment. Concurrently, new approaches have increased the number of compounds that can be tested for activity against these targets. Together, these trends have stimulated the adoption of high-throughput screening as a primary tool for early-stage drug discovery.",

author = "Broach, \{James R.\} and Jeremy Thorner",

year = "1996",

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doi = "10.1038/384014a0",

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journal = "Nature",

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T1 - High-throughput screening for drug discovery

AU - Broach, James R.

AU - Thorner, Jeremy

PY - 1996/11/7

Y1 - 1996/11/7

N2 - Recent progress in elucidating the mechanisms underlying human disease has dramatically increased the number of protein targets available for potential drug treatment. Concurrently, new approaches have increased the number of compounds that can be tested for activity against these targets. Together, these trends have stimulated the adoption of high-throughput screening as a primary tool for early-stage drug discovery.

AB - Recent progress in elucidating the mechanisms underlying human disease has dramatically increased the number of protein targets available for potential drug treatment. Concurrently, new approaches have increased the number of compounds that can be tested for activity against these targets. Together, these trends have stimulated the adoption of high-throughput screening as a primary tool for early-stage drug discovery.

UR - https://www.scopus.com/pages/publications/16044369786

UR - https://www.scopus.com/pages/publications/16044369786#tab=citedBy

U2 - 10.1038/384014a0

DO - 10.1038/384014a0

M3 - Review article

C2 - 8895594

SN - 0028-0836

VL - 384

SP - 14

EP - 16

JO - Nature

JF - Nature

IS - 6604 SUPPL.

ER -

High-throughput screening for drug discovery

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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