Highly sensitive determination of niclosamide based on chitosan functionalized carbon nanotube/carbon black scaffolds with interconnected long- and short-range conductive network

Cuiling Wang, Fang Li, Jinna Li, Liusu Cui, Jiateng Zhong, Hongyuan Zhao, Sridhar Komarneni

Research output: Contribution to journalArticlepeer-review

7 Scopus citations

Abstract

A highly sensitive electrochemical sensor was successfully fabricated for the determination of niclosamide (NA) based on the chitosan (CTS) functionalized carbon nanotube@carbon black scaffolds (CNT@CBS) nanocomposite modified glassy carbon electrode (GCE). CNT@CBS with interconnected long- and short-range conductive network provided more efficient charge transfer channels and high electrochemical active surface area;CTS not only promoted the uniform dispersion of CNT@CBS but also possessed good biocompatibility, high adsorption capability, and excellent film-forming property. Benefitting from the synergistic effect of CNT@CBS and CTS, the CNT@CBS@CTS/GCE sensor showed a low limit of detection of 4.3 nM (Linear NA concentration: 0.01–10 μM). When applied for the NA detection in real samples, the fabricated sensor presented good practicability with satisfactory RSD values of 2.62%–4.35% and recoveries of 95.6–100.5%.

Original languageEnglish (US)
Pages (from-to)4525-4535
Number of pages11
JournalJournal of Materials Research and Technology
Volume19
DOIs
StatePublished - Jul 1 2022

All Science Journal Classification (ASJC) codes

  • Ceramics and Composites
  • Biomaterials
  • Surfaces, Coatings and Films
  • Metals and Alloys

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