How the science of practice will improve evidence-based care

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4 Scopus citations


This review article analyzes the present evidence-based medicine (EBM) algorithm, compares it to the science of practice (SOP) algorithm, and demonstrates how the SOP can evolve from a quality assurance and quality improvement tool into a clinical research tool. Using appropriately constructed prospective observational databases (PODs), the SOP algorithm can be used to draw causal inferences from nonrandomized data, perform innovative comparative effectiveness research, and generate reliable information that can be used to guide treatment decisions.

Original languageEnglish (US)
Article number202
JournalNeurosurgical focus
Issue number5
StatePublished - May 1 2020

All Science Journal Classification (ASJC) codes

  • Surgery
  • Clinical Neurology


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