Human mitochondrial branched chain aminotransferase: Structural basis for substrate specificity and role of redox active cysteines

Keyphrases

• Amino Acids 100%
• Cysteine 100%
• Redox-active 100%
• Substrate Specificity 100%
• Side Chain 100%
• Branched-chain Aminotransferase 100%
• Ketimines 100%
• Aromatic Amino Acids 50%
• Binding Pocket 50%
• Cysteine Residues 50%
• Van Der Waals Interaction 50%
• Aspartate 50%
• Unfolding Method 50%
• Sequence Conservation 50%
• Control Mechanism 50%
• Reaction Intermediates 50%
• Leucine 50%
• Hydrophobic Binding 50%
• Redox 50%
• Reducing Agent 50%
• Biological Basis 50%
• Pyridoxal 5′-phosphate 50%
• Structural Explanation 50%
• Mammalian Proteins 50%
• Redox Status 50%
• Steric Clash 50%

Biochemistry, Genetics and Molecular Biology

• Amino Acids 100%
• Enzyme Specificity 100%
• Transaminase 100%
• Cysteine 100%
• Enzyme 66%
• Crystal Structure 33%
• Pyridoxal Phosphate 33%
• Isoleucine 33%
• Aspartic Acid 33%
• Alanine 33%