Humoral regulation of sleep

James M. Krueger, Jidong Fang, Michael K. Hansen, Jianyi Zhang, Ferenc Obál

Research output: Contribution to journalArticlepeer-review

46 Scopus citations


Cytokines and hormones, including interleukin-1, tumor necrosis factor, growth hormone-releasing hormone, vasoactive intestinal polypeptide and prolactin, are involved in sleep regulation. These substances enhance sleep, inhibition of them inhibits sleep, and their brain levels vary with sleep. This knowledge helps our understanding of the humoral regulation of sleep.

Original languageEnglish (US)
Pages (from-to)189-194
Number of pages6
JournalNews in Physiological Sciences
Issue number4
StatePublished - Aug 1998

All Science Journal Classification (ASJC) codes

  • Physiology


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