Hybrid approaches to nanometer-scale patterning: Exploiting tailored intermolecular interactions

Thomas J. Mullen, Charan Srinivasan, Mitchell J. Shuster, Mark W. Horn, Anne M. Andrews, Paul S. Weiss

Research output: Contribution to journalReview articlepeer-review

17 Scopus citations


In this perspective, we explore hybrid approaches to nanometer-scale patterning, where the precision of molecular self-assembly is combined with the sophistication and fidelity of lithography. Two areas - improving existing lithographic techniques through self-assembly and fabricating chemically patterned surfaces - will be discussed in terms of their advantages, limitations, applications, and future outlook. The creation of such chemical patterns enables new capabilities, including the assembly of biospecific surfaces to be recognized by, and to capture analytes from, complex mixtures. Finally, we speculate on the potential impact and upcoming challenges of these hybrid strategies.

Original languageEnglish (US)
Pages (from-to)1231-1240
Number of pages10
JournalJournal of Nanoparticle Research
Issue number8
StatePublished - Dec 2008

All Science Journal Classification (ASJC) codes

  • Condensed Matter Physics
  • Bioengineering
  • Atomic and Molecular Physics, and Optics
  • General Chemistry
  • General Materials Science
  • Modeling and Simulation


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