Hybrid wound devices for spatiotemporally controlled release kinetics

Ibrahim T. Ozbolat; Bahattin Koc

doi:10.1115/imece2011-62254

Hybrid wound devices for spatiotemporally controlled release kinetics

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

Abstract

This research presents hybrid full thickness wound devices for improved wound healing process. Firstly, a 3D wound bed surface is extracted using imaging study. Then, a 3D lofting process from our previous work [1] is applied to discretize the device geometry into a number of healing regions based on linear wound margin healing fashion. Next, CAD models are developed and inputted into a multi-nozzle rapid prototyping system for biofabrication purposes. Hybrid devices are finally fabricated with varying concentration of biological modifiers and biomaterials to control the release kinetics spatiotemporally. The proposed methodology is implemented and an illustrative hybrid wound device is presented.

Original language	English (US)
Title of host publication	Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology
Publisher	American Society of Mechanical Engineers (ASME)
Pages	425-427
Number of pages	3
ISBN (Print)	9780791854884
DOIs	https://doi.org/10.1115/imece2011-62254
State	Published - 2011
Event	ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 - Denver, CO, United States Duration: Nov 11 2011 → Nov 17 2011

Publication series

Name	ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011
Volume	2

Other

Other	ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011
Country/Territory	United States
City	Denver, CO
Period	11/11/11 → 11/17/11

All Science Journal Classification (ASJC) codes

Mechanical Engineering

Access to Document

10.1115/imece2011-62254

Cite this

Ozbolat, I. T., & Koc, B. (2011). Hybrid wound devices for spatiotemporally controlled release kinetics. In Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology (pp. 425-427). (ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011; Vol. 2). American Society of Mechanical Engineers (ASME). https://doi.org/10.1115/imece2011-62254

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title = "Hybrid wound devices for spatiotemporally controlled release kinetics",

abstract = "This research presents hybrid full thickness wound devices for improved wound healing process. Firstly, a 3D wound bed surface is extracted using imaging study. Then, a 3D lofting process from our previous work [1] is applied to discretize the device geometry into a number of healing regions based on linear wound margin healing fashion. Next, CAD models are developed and inputted into a multi-nozzle rapid prototyping system for biofabrication purposes. Hybrid devices are finally fabricated with varying concentration of biological modifiers and biomaterials to control the release kinetics spatiotemporally. The proposed methodology is implemented and an illustrative hybrid wound device is presented.",

author = "Ozbolat, {Ibrahim T.} and Bahattin Koc",

year = "2011",

doi = "10.1115/imece2011-62254",

language = "English (US)",

isbn = "9780791854884",

series = "ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011",

publisher = "American Society of Mechanical Engineers (ASME)",

pages = "425--427",

booktitle = "Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology",

note = "ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011 ; Conference date: 11-11-2011 Through 17-11-2011",

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Ozbolat, IT & Koc, B 2011, Hybrid wound devices for spatiotemporally controlled release kinetics. in Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology. ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011, vol. 2, American Society of Mechanical Engineers (ASME), pp. 425-427, ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011, Denver, CO, United States, 11/11/11. https://doi.org/10.1115/imece2011-62254

Hybrid wound devices for spatiotemporally controlled release kinetics. / Ozbolat, Ibrahim T.; Koc, Bahattin.
Biomedical and Biotechnology Engineering; Nanoengineering for Medicine and Biology. American Society of Mechanical Engineers (ASME), 2011. p. 425-427 (ASME 2011 International Mechanical Engineering Congress and Exposition, IMECE 2011; Vol. 2).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution

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AB - This research presents hybrid full thickness wound devices for improved wound healing process. Firstly, a 3D wound bed surface is extracted using imaging study. Then, a 3D lofting process from our previous work [1] is applied to discretize the device geometry into a number of healing regions based on linear wound margin healing fashion. Next, CAD models are developed and inputted into a multi-nozzle rapid prototyping system for biofabrication purposes. Hybrid devices are finally fabricated with varying concentration of biological modifiers and biomaterials to control the release kinetics spatiotemporally. The proposed methodology is implemented and an illustrative hybrid wound device is presented.

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Hybrid wound devices for spatiotemporally controlled release kinetics

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All Science Journal Classification (ASJC) codes

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