Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

T. Takatani-Nakase; M. Katayama; C. Matsui; K. Hanaoka; A. J. Van Der Vlies; K. Takahashi; I. Nakase; U. Hasegawa

doi:10.1039/c7mb00191f

Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

T. Takatani-Nakase, M. Katayama, C. Matsui, K. Hanaoka, A. J. Van Der Vlies, K. Takahashi, I. Nakase, U. Hasegawa

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

23 Scopus citations

Abstract

Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H₂S donor micelle releases H₂S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

Original language	English (US)
Pages (from-to)	1705-1708
Number of pages	4
Journal	Molecular BioSystems
Volume	13
Issue number	9
DOIs	https://doi.org/10.1039/c7mb00191f
State	Published - 2017

All Science Journal Classification (ASJC) codes

Biotechnology
Molecular Biology

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10.1039/c7mb00191f

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title = "Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death",

abstract = "Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.",

author = "T. Takatani-Nakase and M. Katayama and C. Matsui and K. Hanaoka and {Van Der Vlies}, {A. J.} and K. Takahashi and I. Nakase and U. Hasegawa",

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year = "2017",

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T1 - Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

AU - Takatani-Nakase, T.

AU - Katayama, M.

AU - Matsui, C.

AU - Hanaoka, K.

AU - Van Der Vlies, A. J.

AU - Takahashi, K.

AU - Nakase, I.

AU - Hasegawa, U.

PY - 2017

Y1 - 2017

N2 - Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

AB - Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

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U2 - 10.1039/c7mb00191f

DO - 10.1039/c7mb00191f

M3 - Article

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EP - 1708

JO - Molecular BioSystems

JF - Molecular BioSystems

IS - 9

ER -

Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

Abstract

All Science Journal Classification (ASJC) codes

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