Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

T. Takatani-Nakase; M. Katayama; C. Matsui; K. Hanaoka; A. J. Van Der Vlies; K. Takahashi; I. Nakase; U. Hasegawa

doi:10.1039/c7mb00191f

Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

T. Takatani-Nakase
, M. Katayama
, C. Matsui
, K. Hanaoka
, A. J. Van Der Vlies
, K. Takahashi
, I. Nakase
, U. Hasegawa

Materials Science and Engineering

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H₂S donor micelle releases H₂S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

Original language	English (US)
Pages (from-to)	1705-1708
Number of pages	4
Journal	Molecular BioSystems
Volume	13
Issue number	9
DOIs	https://doi.org/10.1039/c7mb00191f
State	Published - 2017

All Science Journal Classification (ASJC) codes

Biotechnology
Molecular Biology

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10.1039/c7mb00191f

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title = "Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death",

abstract = "Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.",

author = "T. Takatani-Nakase and M. Katayama and C. Matsui and K. Hanaoka and \{Van Der Vlies\}, \{A. J.\} and K. Takahashi and I. Nakase and U. Hasegawa",

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year = "2017",

doi = "10.1039/c7mb00191f",

language = "English (US)",

volume = "13",

pages = "1705--1708",

journal = "Molecular BioSystems",

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publisher = "Royal Society of Chemistry",

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TY - JOUR

T1 - Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

AU - Takatani-Nakase, T.

AU - Katayama, M.

AU - Matsui, C.

AU - Hanaoka, K.

AU - Van Der Vlies, A. J.

AU - Takahashi, K.

AU - Nakase, I.

AU - Hasegawa, U.

PY - 2017

Y1 - 2017

N2 - Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

AB - Hydrogen sulfide, an important gaseous signaling molecule in the human body, is known to protect cardiomyocytes from ischemia, a condition characterized by insufficient oxygen supply to the cells. Here we show that a nanosized H2S donor micelle releases H2S intracellularly and prevents cardiomyocyte apoptosis in an in vitro ischemia model.

UR - https://www.scopus.com/pages/publications/85028077638

UR - https://www.scopus.com/pages/publications/85028077638#tab=citedBy

U2 - 10.1039/c7mb00191f

DO - 10.1039/c7mb00191f

M3 - Article

AN - SCOPUS:85028077638

SN - 1742-206X

VL - 13

SP - 1705

EP - 1708

JO - Molecular BioSystems

JF - Molecular BioSystems

IS - 9

ER -

Hydrogen sulfide donor micelles protect cardiomyocytes from ischemic cell death

Abstract

All Science Journal Classification (ASJC) codes

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