Abstract
This article describes the structure, function and metabolism of lipoprotein particles, which are complex macromolecules involved in the transport of lipids in the body. The primary lipids that are packaged in lipoproteins are cholesterol and triglycerides. Metabolism of lipoprotein particle involves many metabolic pathways that function to regulates plasma levels of cholesterol and triglycerides. Disorders in these pathways lead to hypercholesterolemia and hypertriglyceridemia, both of which increase risk of coronary artery diseases (CAD). Major causes of hyperlipidemia include genetics and lifestyle. The familial dyslipidemias have been classified by Fredrickson, Levy and Lees. All dyslipidemias benefit from healthy lifestyle practices, including a heart healthy dietary pattern. Decreasing elevated cholesterol and triglyceride levels decreases risk of CAD.
Original language | English (US) |
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Title of host publication | Encyclopedia of Human Nutrition |
Subtitle of host publication | Volume 1-4, Fourth Edition |
Publisher | Elsevier |
Pages | 361-379 |
Number of pages | 19 |
Volume | 1-4 |
ISBN (Electronic) | 9780323908160 |
DOIs | |
State | Published - Jan 1 2023 |
All Science Journal Classification (ASJC) codes
- General Engineering
- General Agricultural and Biological Sciences