Hypertrophic cardiomyopathy: Pathophysiology, diagnosis, and treatment

Eric Popjes, M. St J Sutton

Research output: Contribution to journalReview articlepeer-review

10 Scopus citations


Hypertrophic cardiomyopathy is one of the most common inherited cardiovascular diseases and is characterized by a heterogeneous appearance and natural history. Although previously thought to be a disease of the young, HCM is frequently diagnosed in patients over age 50. A careful history and physical examination and readily available non-invasive testing will diagnose most cases, but genetic testing can identify those not expressing the typical phenotype. Treatment of symptomatic patients is targeted toward improving LV diastolic function; for patients with the obstructive form of HCM, treatement involves relieving outflow tract obstruction. Identification of those at risk for sudden death may require consideration of prophylactic defibrillator placement.

Original languageEnglish (US)
Pages (from-to)41-46
Number of pages6
Issue number3
StatePublished - Mar 1 2003

All Science Journal Classification (ASJC) codes

  • Geriatrics and Gerontology


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