Hypertrophic, Hypersecretory Protein-losing Gastropathy

Bergein F. Overholt, Graham H. Jeffries

Research output: Contribution to journalArticlepeer-review

55 Scopus citations


A patient who presented with the clinical manifestations of hypoproteinemia and in whom gastric hyperrugosity was associated with excessive gastric protein loss and acid hypersecretion is reported. Atropine sulfate markedly reduced both the hypersecretion and gastric protein loss. It is suggested that anticholinergic therapy be considered in any patient with a protein-losing gastropathy of nonmalignant etiology in whom high, normal, and perhaps even subnormal acid secretion is found following maximal histamine stimulation.

Original languageEnglish (US)
Pages (from-to)80-87
Number of pages8
Issue number1
StatePublished - 1970

All Science Journal Classification (ASJC) codes

  • Hepatology
  • Gastroenterology


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