TY - JOUR
T1 - Hypertrophic olivary degeneration
T2 - Case series and review of literature
AU - Sabat, Shyamsunder
AU - Mannering, Neil
AU - Agarwal, Amit
N1 - Publisher Copyright:
© 2016 Elsevier B.V.
PY - 2016/11/15
Y1 - 2016/11/15
N2 - Hypertrophic Olivary Degeneration (HOD) is a rare neurological condition caused by trans-synaptic degeneration in the brainstem and cerebellum, resulting in varied clinical symptoms, classical being palatal tremors, along with characteristic imaging presentation. Large number of pathologic lesions can cause this condition, ranging from ischemic stroke to neoplasm. The most common conditions include hemorrhage, vascular malformations and infarct. Magnetic resonance scan (MRI) is the imaging modality of choice which shows signal changes with hypertrophy of the inferior olivary nucleus, as well as the primary underlying pathology. Through this pictorial essay, we present the imaging and clinical findings in a number of patients with HOD secondary to varied causes and explain the mechanism behind the changes.
AB - Hypertrophic Olivary Degeneration (HOD) is a rare neurological condition caused by trans-synaptic degeneration in the brainstem and cerebellum, resulting in varied clinical symptoms, classical being palatal tremors, along with characteristic imaging presentation. Large number of pathologic lesions can cause this condition, ranging from ischemic stroke to neoplasm. The most common conditions include hemorrhage, vascular malformations and infarct. Magnetic resonance scan (MRI) is the imaging modality of choice which shows signal changes with hypertrophy of the inferior olivary nucleus, as well as the primary underlying pathology. Through this pictorial essay, we present the imaging and clinical findings in a number of patients with HOD secondary to varied causes and explain the mechanism behind the changes.
UR - http://www.scopus.com/inward/record.url?scp=84989172777&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84989172777&partnerID=8YFLogxK
U2 - 10.1016/j.jns.2016.09.055
DO - 10.1016/j.jns.2016.09.055
M3 - Review article
C2 - 27772756
AN - SCOPUS:84989172777
SN - 0022-510X
VL - 370
SP - 180
EP - 186
JO - Journal of the neurological sciences
JF - Journal of the neurological sciences
ER -