Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion

Raymond L. Funk; Craig J. Mossman; Wayne E. Zeller

doi:10.1016/S0040-4039(01)81136-9

Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion

Raymond L. Funk, Craig J. Mossman, Wayne E. Zeller

Chemistry

Research output: Contribution to journal › Article › peer-review

24 Scopus citations

Abstract

The synthesis of the hexahydronaphthalene segment (4) of compactin (1) has been accomplished in a short sequence (8 steps from 9) featuring the intramolecular Diels-Alder cycloaddition of 7b.

Original language	English (US)
Pages (from-to)	1655-1658
Number of pages	4
Journal	Tetrahedron Letters
Volume	25
Issue number	16
DOIs	https://doi.org/10.1016/S0040-4039(01)81136-9
State	Published - 1984

All Science Journal Classification (ASJC) codes

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)81136-9

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title = "Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion",

abstract = "The synthesis of the hexahydronaphthalene segment (4) of compactin (1) has been accomplished in a short sequence (8 steps from 9) featuring the intramolecular Diels-Alder cycloaddition of 7b.",

author = "Funk, {Raymond L.} and Mossman, {Craig J.} and Zeller, {Wayne E.}",

year = "1984",

doi = "10.1016/S0040-4039(01)81136-9",

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journal = "Tetrahedron Letters",

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T1 - Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion

AU - Funk, Raymond L.

AU - Mossman, Craig J.

AU - Zeller, Wayne E.

PY - 1984

Y1 - 1984

N2 - The synthesis of the hexahydronaphthalene segment (4) of compactin (1) has been accomplished in a short sequence (8 steps from 9) featuring the intramolecular Diels-Alder cycloaddition of 7b.

AB - The synthesis of the hexahydronaphthalene segment (4) of compactin (1) has been accomplished in a short sequence (8 steps from 9) featuring the intramolecular Diels-Alder cycloaddition of 7b.

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U2 - 10.1016/S0040-4039(01)81136-9

DO - 10.1016/S0040-4039(01)81136-9

M3 - Article

AN - SCOPUS:0021366283

SN - 0040-4039

VL - 25

SP - 1655

EP - 1658

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 16

ER -

Hypocholesterolemic agent compactin. an alternative diels-alder strategy for the synthesis of the hexahydronaphthalene portion

Abstract

All Science Journal Classification (ASJC) codes

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