TY - JOUR
T1 - Hypoglycemia as the onset manifestation of somatostatinoma
T2 - A case report and review of the literature
AU - Zhang, Wei
AU - Yang, Guoji
AU - Li, Hongwei
AU - Wang, Hanmin
AU - Jin, Yumei
AU - Chen, Haobin
AU - Chen, Weiwen
AU - Bellanti, Joseph A.
AU - Zheng, Song Guo
N1 - Funding Information:
This work was supported by grant from the Department of Science and Technology of Yunnan Province-Kunming Medical University Basic Research (2017FE467(-105)) and project from the Workstation for Academicians and Experts of Yunnan Province.
Publisher Copyright:
© 2017, E-Century Publishing Corporation. All rights reserved.
PY - 2017/11/30
Y1 - 2017/11/30
N2 - Somatostatinoma is a rare pancreatic tumor characterized by diabetes mellitus, cholelithiases, and diarrhea. Although hypoglycemia is a distinctively unusual manifestation of the condition, most patients are symptomatic at the time of diagnosis. However, since the tumor is slow growing and symptoms are often not present for several years before diagnosis, the disease is often quite advanced by the time, patients seek medical attention and preoperative diagnosis is therefore often difficult. We reported a 30-year-old man who presented with hypoglycemia, hypersomnia and hyperinsulinemia. Magnetic resonance imaging (MRI) demonstrated a low-density mass in the head of the pancreas suggestive of a malignancy that was definitively identified as a somatostatinoma by immunohistochemical staining of a biopsy specimen.
AB - Somatostatinoma is a rare pancreatic tumor characterized by diabetes mellitus, cholelithiases, and diarrhea. Although hypoglycemia is a distinctively unusual manifestation of the condition, most patients are symptomatic at the time of diagnosis. However, since the tumor is slow growing and symptoms are often not present for several years before diagnosis, the disease is often quite advanced by the time, patients seek medical attention and preoperative diagnosis is therefore often difficult. We reported a 30-year-old man who presented with hypoglycemia, hypersomnia and hyperinsulinemia. Magnetic resonance imaging (MRI) demonstrated a low-density mass in the head of the pancreas suggestive of a malignancy that was definitively identified as a somatostatinoma by immunohistochemical staining of a biopsy specimen.
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M3 - Article
AN - SCOPUS:85036505150
SN - 1940-5901
VL - 10
SP - 15666
EP - 15671
JO - International Journal of Clinical and Experimental Medicine
JF - International Journal of Clinical and Experimental Medicine
IS - 11
ER -
