Hypoxic-ischemic encephalopathy: Therapeutic approaches against microvascular injury, and role of neutrophils, PAF, and free radicals

C. Palmer

doi:10.1016/s0095-5108(18)30294-x

Hypoxic-ischemic encephalopathy: Therapeutic approaches against microvascular injury, and role of neutrophils, PAF, and free radicals

C. Palmer

Research output: Contribution to journal › Review article › peer-review

115 Scopus citations

Abstract

The asphyxiated newborn undergoes progressive brain damage even after resuscitation. This article reviews the microvascular events that contribute to evolving brain injury. The role of neutrophils, platelet-activating factor (PAF), and free radicals is stressed as pivotal mechanisms of injury and opportunities for therapeutic intervention.

Original language	English (US)
Pages (from-to)	481-517
Number of pages	37
Journal	Clinics in Perinatology
Volume	22
Issue number	2
DOIs	https://doi.org/10.1016/s0095-5108(18)30294-x
State	Published - 1995

All Science Journal Classification (ASJC) codes

Pediatrics, Perinatology, and Child Health
Obstetrics and Gynecology

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10.1016/s0095-5108(18)30294-x

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title = "Hypoxic-ischemic encephalopathy: Therapeutic approaches against microvascular injury, and role of neutrophils, PAF, and free radicals",

abstract = "The asphyxiated newborn undergoes progressive brain damage even after resuscitation. This article reviews the microvascular events that contribute to evolving brain injury. The role of neutrophils, platelet-activating factor (PAF), and free radicals is stressed as pivotal mechanisms of injury and opportunities for therapeutic intervention.",

author = "C. Palmer",

year = "1995",

doi = "10.1016/s0095-5108(18)30294-x",

language = "English (US)",

volume = "22",

pages = "481--517",

journal = "Clinics in Perinatology",

issn = "0095-5108",

publisher = "W.B. Saunders",

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T1 - Hypoxic-ischemic encephalopathy

T2 - Therapeutic approaches against microvascular injury, and role of neutrophils, PAF, and free radicals

AU - Palmer, C.

PY - 1995

Y1 - 1995

N2 - The asphyxiated newborn undergoes progressive brain damage even after resuscitation. This article reviews the microvascular events that contribute to evolving brain injury. The role of neutrophils, platelet-activating factor (PAF), and free radicals is stressed as pivotal mechanisms of injury and opportunities for therapeutic intervention.

AB - The asphyxiated newborn undergoes progressive brain damage even after resuscitation. This article reviews the microvascular events that contribute to evolving brain injury. The role of neutrophils, platelet-activating factor (PAF), and free radicals is stressed as pivotal mechanisms of injury and opportunities for therapeutic intervention.

UR - https://www.scopus.com/pages/publications/0029028282

UR - https://www.scopus.com/pages/publications/0029028282#tab=citedBy

U2 - 10.1016/s0095-5108(18)30294-x

DO - 10.1016/s0095-5108(18)30294-x

M3 - Review article

C2 - 7671548

AN - SCOPUS:0029028282

SN - 0095-5108

VL - 22

SP - 481

EP - 517

JO - Clinics in Perinatology

JF - Clinics in Perinatology

IS - 2

ER -

Hypoxic-ischemic encephalopathy: Therapeutic approaches against microvascular injury, and role of neutrophils, PAF, and free radicals

Abstract

All Science Journal Classification (ASJC) codes

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