I Heard These Medications Give You Cancer. Is That True? Risks of Malignancy with IBD Therapy

Ryan R. Gaffney, Andrew Tinsley

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

“Thiopurines (azathioprine and mercaptopurine) and biologic anti-TNF agents (infliximab, adalimumab, certolizumab, and golimumab) are some of the most effective medications that we have for treating inflammatory bowel disease. However, it is important to recognize that these therapies have been associated with an increase in the risk of developing certain cancers including lymphoma and skin cancer. Fortunately, the total number of people who develop these cancers while on therapy is very small. There is also little evidence that thiopurines and anti-TNF drugs significantly increase the risk of other types of cancers. Before initiating treatment with these types of medications, we need to review your cancer risks and weigh them against the considerable benefits these therapies can offer.”

Original languageEnglish (US)
Title of host publicationInflammatory Bowel Disease
Subtitle of host publicationA Point of Care Clinical Guide
PublisherSpringer International Publishing
Pages135-140
Number of pages6
ISBN (Electronic)9783319140728
ISBN (Print)9783319140711
DOIs
StatePublished - Jan 1 2015

All Science Journal Classification (ASJC) codes

  • General Medicine

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