Identification of a cellulose synthase-associated protein required for cellulose biosynthesis

Ying Gu, Nick Kaplinsky, Martin Bringmann, Alex Cobb, Andrew Carroll, Arun Sampathkumar, Tobias I. Baskin, Staffan Persson, Chris R. Somerville

Research output: Contribution to journalArticlepeer-review

193 Scopus citations


Cellulose synthase-interactive protein 1 (CSI1) was identified in a two-hybrid screen for proteins that interact with cellulose synthase (CESA) isoforms involved in primary plant cell wall synthesis. CSI1 encodes a 2,150-amino acid protein that contains 10 predicted Armadillo repeats and a C2 domain. Mutations in CSI1 cause defective cell elongation in hypocotyls and roots and reduce cellulose content. CSI1 is associated with CESA complexes, and csi1 mutants affect the distribution and movement of CESA complexes in the plasma membrane.

Original languageEnglish (US)
Pages (from-to)12866-12871
Number of pages6
JournalProceedings of the National Academy of Sciences of the United States of America
Issue number29
StatePublished - Jul 20 2010

All Science Journal Classification (ASJC) codes

  • General


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