Identification of membrane curvature sensing motifs essential for VPS37A phagophore recruitment and autophagosome closure

Yansheng Ye, Xinwen Liang, Guifang Wang, Maria C. Bewley, Kouta Hamamoto, Xiaoming Liu, John Flanagan, Hong-Gang Wang, Yoshinori Takahashi, Fang Tian

Research output: Contribution to journalArticlepeer-review

Abstract

Two membrane curvature-sensitive motifs in unstructured regions of the N-terminal domain of VPS37A are required for its phagophore recruitment and autophagosome closure.

Original languageEnglish (US)
Article number334
JournalCommunications Biology
Volume7
Issue number1
DOIs
StatePublished - Dec 2024

All Science Journal Classification (ASJC) codes

  • Medicine (miscellaneous)
  • General Biochemistry, Genetics and Molecular Biology
  • General Agricultural and Biological Sciences

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