TY - JOUR
T1 - Idiopathic hypertrophic spinal pachymeningitis
T2 - Report of 3 cases
AU - Ranasinghe, Moksha G.
AU - Zalatimo, Omar
AU - Rizk, Elias
AU - Specht, Charles
AU - Reiter, G. Timothy
AU - Harbaugh, Robert
AU - Sheehan, Jonas
N1 - Copyright:
Copyright 2011 Elsevier B.V., All rights reserved.
PY - 2011/8
Y1 - 2011/8
N2 - Spinal idiopathic hypertrophic pachymeningitis (IHP) is a rare, chronic, nonspecific, granulomatous inflammatory disorder of the dura with unknown etiology. It can cause a localized or diffuse thickening of the dura mater with compression of the spinal canal and possible myelopathic symptoms. The authors report 3 consecutive cases of spinal IHP with a review of the literature. The diagnosis of spinal IHP was based on biopsy and pathological confirmation. Typical MR imaging findings suggestive of spinal IHP were noted in all cases. The clinical course may be marked by deterioration despite conservative therapy and may require surgical intervention to prevent irreversible neurological damage. Therefore, prompt diagnosis and institution of proper treatment is critical.
AB - Spinal idiopathic hypertrophic pachymeningitis (IHP) is a rare, chronic, nonspecific, granulomatous inflammatory disorder of the dura with unknown etiology. It can cause a localized or diffuse thickening of the dura mater with compression of the spinal canal and possible myelopathic symptoms. The authors report 3 consecutive cases of spinal IHP with a review of the literature. The diagnosis of spinal IHP was based on biopsy and pathological confirmation. Typical MR imaging findings suggestive of spinal IHP were noted in all cases. The clinical course may be marked by deterioration despite conservative therapy and may require surgical intervention to prevent irreversible neurological damage. Therefore, prompt diagnosis and institution of proper treatment is critical.
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U2 - 10.3171/2011.4.SPINE1037
DO - 10.3171/2011.4.SPINE1037
M3 - Article
C2 - 21568651
AN - SCOPUS:80051686518
SN - 1547-5654
VL - 15
SP - 195
EP - 201
JO - Journal of Neurosurgery: Spine
JF - Journal of Neurosurgery: Spine
IS - 2
ER -