IgE myeloma with osteoblastic lesions

J. S. Rogers, J. Spahr, D. M. Judge, L. A. Varano, M. E. Eyster

Research output: Contribution to journalArticlepeer-review

22 Scopus citations


A 69 yr old man with persistent anemia had multiple myeloma with an IgE type kappa M component and Bence Jones proteinuria. Bone X rays revealed occasional lytic lesions associated with a diffuse sclerotic reaction throughout the skeleton. Special bone histologic studies utilizing tetracycline labeling, undecalcified sections, and microradiography confirmed active osteoblastic activity. This case is compared with the 4 (allegedly) previously reported cases of IgE myeloma, one of which also had osteosclerosis.

Original languageEnglish (US)
Pages (from-to)295-299
Number of pages5
Issue number2
StatePublished - 1977

All Science Journal Classification (ASJC) codes

  • Biochemistry
  • Immunology
  • Hematology
  • Cell Biology


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