IL-17: A key player in the P. acnes inflammatory cascade?

Diane M. Thiboutot; Alison M. Layton; E. Anne Eady

doi:10.1038/jid.2013.400

IL-17: A key player in the P. acnes inflammatory cascade?

Diane M. Thiboutot
, Alison M. Layton
, E. Anne Eady

Research output: Contribution to journal › Comment/debate › peer-review

50 Scopus citations

Abstract

Recent advances in our understanding of inflammatory skin diseases now afford an opportunity to delve deeper into microbial/host interactions in acne. Agak et al. report that Propionibacterium acnes induces IL-17 expression in peripheral blood mononuclear cells and present new evidence that IL-17+ cells are found in the perifollicular infiltrate of comedones. Additional studies are needed to assess the clinical relevance of IL-17 in acne.

Original language	English (US)
Pages (from-to)	307-310
Number of pages	4
Journal	Journal of Investigative Dermatology
Volume	134
Issue number	2
DOIs	https://doi.org/10.1038/jid.2013.400
State	Published - Feb 2014

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Dermatology
Cell Biology

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10.1038/jid.2013.400

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title = "IL-17: A key player in the P. acnes inflammatory cascade?",

abstract = "Recent advances in our understanding of inflammatory skin diseases now afford an opportunity to delve deeper into microbial/host interactions in acne. Agak et al. report that Propionibacterium acnes induces IL-17 expression in peripheral blood mononuclear cells and present new evidence that IL-17+ cells are found in the perifollicular infiltrate of comedones. Additional studies are needed to assess the clinical relevance of IL-17 in acne.",

author = "Thiboutot, \{Diane M.\} and Layton, \{Alison M.\} and Eady, \{E. Anne\}",

year = "2014",

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T2 - A key player in the P. acnes inflammatory cascade?

AU - Thiboutot, Diane M.

AU - Layton, Alison M.

AU - Eady, E. Anne

PY - 2014/2

Y1 - 2014/2

N2 - Recent advances in our understanding of inflammatory skin diseases now afford an opportunity to delve deeper into microbial/host interactions in acne. Agak et al. report that Propionibacterium acnes induces IL-17 expression in peripheral blood mononuclear cells and present new evidence that IL-17+ cells are found in the perifollicular infiltrate of comedones. Additional studies are needed to assess the clinical relevance of IL-17 in acne.

AB - Recent advances in our understanding of inflammatory skin diseases now afford an opportunity to delve deeper into microbial/host interactions in acne. Agak et al. report that Propionibacterium acnes induces IL-17 expression in peripheral blood mononuclear cells and present new evidence that IL-17+ cells are found in the perifollicular infiltrate of comedones. Additional studies are needed to assess the clinical relevance of IL-17 in acne.

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UR - https://www.scopus.com/pages/publications/84892720949#tab=citedBy

U2 - 10.1038/jid.2013.400

DO - 10.1038/jid.2013.400

M3 - Comment/debate

C2 - 24424453

AN - SCOPUS:84892720949

SN - 0022-202X

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SP - 307

EP - 310

JO - Journal of Investigative Dermatology

JF - Journal of Investigative Dermatology

IS - 2

ER -

IL-17: A key player in the P. acnes inflammatory cascade?

Abstract

All Science Journal Classification (ASJC) codes

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