@inproceedings{668085146cdd41ee8129a3594a4a5228,
title = "Image-based numerical modeling of HIFU-induced lesions",
abstract = "Atherosclerosis is a chronic vascular disease affecting large and medium sized arteries. Several treatment options are already available for treatment of this disease. Targeting atherosclerotic plaques by high intensity focused ultrasound (HIFU) using dual mode ultrasound arrays (DMUA) was recently introduced in literature. We present a finite difference time domain (FDTD) simulation modeling of the wave propagation in heterogeneous medium from the surface of a 3.5MHz array prototype with 32-elements. After segmentation of the ultrasound image obtained for the treatment region in-vivo, we integrated this anatomical information into our simulation to account for different parameters that may be caused by these multi-region anatomical complexities. The simulation program showed that HIFU was able to induce damage in the prefocal region instead of the target area. The HIFU lesions, as predicted by our simulation, were well correlated with the actual damage detected in histology.",
author = "Almekkaway, {Mohamed K.} and Shehata, {Islam A.} and Alyona Haritonova and John Ballard and Andrew Casper and Emad Ebbini",
note = "Publisher Copyright: {\textcopyright} 2017 Author(s).; 13th International Symposium on Therapeutic Ultrasound, ISTU 2013 ; Conference date: 12-05-2013 Through 15-05-2013",
year = "2017",
month = mar,
day = "1",
doi = "10.1063/1.4976591",
language = "English (US)",
series = "AIP Conference Proceedings",
publisher = "American Institute of Physics Inc.",
editor = "Fowlkes, {J. Brian} and Salgaonkar, {Vasant A.}",
booktitle = "Proceedings from the 13th International Symposium on Therapeutic Ultrasound",
}