Imaging macrophages in trehalose with SIMS

S. A. Parry; M. E. Kurczy; X. Fan; M. S. Halleck; R. A. Schlegel; N. Winograd

doi:10.1016/j.apsusc.2008.05.251

Imaging macrophages in trehalose with SIMS

S. A. Parry, M. E. Kurczy, X. Fan, M. S. Halleck, R. A. Schlegel, N. Winograd

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9 Scopus citations

Abstract

Phagocytosis is a major component of the animal immune system where apoptotic cellular material, metabolites, and waste are safely processed. Further, efficient phagocytosis by macrophages is key to maintaining healthy vascular systems and preventing atherosclerosis. Single-cell images of macrophage phagocytosis of red blood cells, RBCs, and polystyrene microspheres have been chemically mapped with TOF-SIMS. We demonstrate here cholesterol and phosphocholine localizations as relative to time and activity.

Original language	English (US)
Pages (from-to)	929-933
Number of pages	5
Journal	Applied Surface Science
Volume	255
Issue number	4
DOIs	https://doi.org/10.1016/j.apsusc.2008.05.251
State	Published - Dec 15 2008

All Science Journal Classification (ASJC) codes

General Chemistry
Condensed Matter Physics
General Physics and Astronomy
Surfaces and Interfaces
Surfaces, Coatings and Films

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10.1016/j.apsusc.2008.05.251

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abstract = "Phagocytosis is a major component of the animal immune system where apoptotic cellular material, metabolites, and waste are safely processed. Further, efficient phagocytosis by macrophages is key to maintaining healthy vascular systems and preventing atherosclerosis. Single-cell images of macrophage phagocytosis of red blood cells, RBCs, and polystyrene microspheres have been chemically mapped with TOF-SIMS. We demonstrate here cholesterol and phosphocholine localizations as relative to time and activity.",

author = "Parry, {S. A.} and Kurczy, {M. E.} and X. Fan and Halleck, {M. S.} and Schlegel, {R. A.} and N. Winograd",

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AU - Parry, S. A.

AU - Kurczy, M. E.

AU - Fan, X.

AU - Halleck, M. S.

AU - Schlegel, R. A.

AU - Winograd, N.

PY - 2008/12/15

Y1 - 2008/12/15

N2 - Phagocytosis is a major component of the animal immune system where apoptotic cellular material, metabolites, and waste are safely processed. Further, efficient phagocytosis by macrophages is key to maintaining healthy vascular systems and preventing atherosclerosis. Single-cell images of macrophage phagocytosis of red blood cells, RBCs, and polystyrene microspheres have been chemically mapped with TOF-SIMS. We demonstrate here cholesterol and phosphocholine localizations as relative to time and activity.

AB - Phagocytosis is a major component of the animal immune system where apoptotic cellular material, metabolites, and waste are safely processed. Further, efficient phagocytosis by macrophages is key to maintaining healthy vascular systems and preventing atherosclerosis. Single-cell images of macrophage phagocytosis of red blood cells, RBCs, and polystyrene microspheres have been chemically mapped with TOF-SIMS. We demonstrate here cholesterol and phosphocholine localizations as relative to time and activity.

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SP - 929

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JO - Applied Surface Science

JF - Applied Surface Science

IS - 4

ER -

Imaging macrophages in trehalose with SIMS

Abstract

All Science Journal Classification (ASJC) codes

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