Imidazo[4,5-d]thiazolo[5,4-b]pyridine based inhibitors of IKK2: Synthesis, SAR, PK/PD and activity in a preclinical model of rheumatoid arthritis

Alaric J. Dyckman, Charles M. Langevine, Claude Quesnelle, James Kempson, Junqing Guo, Patrice Gill, Steven H. Spergel, Scott H. Watterson, Tianle Li, David S. Nirschl, Kathleen M. Gillooly, Mark A. Pattoli, Kim W. McIntyre, Laishun Chen, Murray McKinnon, John H. Dodd, Joel C. Barrish, James R. Burke, William J. Pitts

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