Immunoinformatics Cyberinfrastructure for Modeling and Analytics

Stefan Hoops, Bruno W. Sobral, Pawel Michalak, Vida Abedi, Barbara Kronsteiner, Raquel Hontecillas, Monica Viladomiu, Josep Bassaganya-Riera

Research output: Chapter in Book/Report/Conference proceedingChapter


The twenty-first century immunology research requires the collaboration of a team of scientists with different backgrounds and expertise including immunologists, biochemists, molecular biologists, bioinformaticians, statisticians, and mathematicians to address important immunological questions. For this team to work seamlessly and efficiently we require an immunoinformatics cyberinfrastructure that supports the collection of experimental data (. in vitro, ex vivo, preclinical, and clinical) and metadata, the aggregation, analysis and visualization of this data and presentation of analysis results, the model building, calibration and analysis process, and finally the maintenance of quality assurance. This chapter describes the cyberinfrastructure required to integrate computational modeling, big data analytics, portal science, and procedural knowledge to engineer synthetic systems-wide information processing representations of immune responses.

Original languageEnglish (US)
Title of host publicationComputational Immunology
Subtitle of host publicationModels and Tools
PublisherElsevier Inc.
Number of pages17
ISBN (Electronic)9780128037157
ISBN (Print)9780128036976
StatePublished - 2016

All Science Journal Classification (ASJC) codes

  • General Medicine


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