TY - JOUR
T1 - Immunoreactive Met-Enkephalin in the Canine Adrenal; Response to Acute Hypovolemic Stress
AU - Farrell, Leo D.
AU - Harrison, Timothy S.
AU - Demers, Laurence M.
PY - 1983/9
Y1 - 1983/9
N2 - Immunoreactive met-enkephalin was measured in the adrenal, kidney, liver, and intestine of the dog using radioimmunoassay. Adrenal tissue concentrations were 20 to 200-fold higher than the other tissues studied. In response to acute hypovolemic stress, the concentration of met-enkephalin in the adrenal vein of the dog increased 6-fold over basal peripheral arterial levels. These results suggest that the canine adrenal gland is a rich source of this opioid peptide and that the adrenal releases met-enkephalin in response to acute stress.
AB - Immunoreactive met-enkephalin was measured in the adrenal, kidney, liver, and intestine of the dog using radioimmunoassay. Adrenal tissue concentrations were 20 to 200-fold higher than the other tissues studied. In response to acute hypovolemic stress, the concentration of met-enkephalin in the adrenal vein of the dog increased 6-fold over basal peripheral arterial levels. These results suggest that the canine adrenal gland is a rich source of this opioid peptide and that the adrenal releases met-enkephalin in response to acute stress.
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U2 - 10.3181/00379727-173-41680
DO - 10.3181/00379727-173-41680
M3 - Article
C2 - 6889316
AN - SCOPUS:0020503705
SN - 0037-9727
VL - 173
SP - 515
EP - 518
JO - Proceedings of the Society for Experimental Biology and Medicine
JF - Proceedings of the Society for Experimental Biology and Medicine
IS - 4
ER -