Impact of distant ischemic preconditioning on oxidative stress in cardiosurgical patients

V. V. Lomivorotov, V. A. Shmirev, D. N. Ponomarev, S. M. Efremov, A. N. Shilova

Research output: Contribution to journalArticlepeer-review

Abstract

Impact of distant ischemic preconditioning (DIP) on development of oxidative stress and severity of myocardial injury was studied in 88 patients undergoing myocardial revascularization under artificial circulation. In DIP group patients three times during 5 minutes underwent cuff inflation on the shoulder (up to 200 mm Hg) for non-invasive estimation of blood pressure with further reperfusion during 5 minutes. It is shown that DIP doesn’t have any impact on degree of myocardial injury and oxidative stress in patients with normal myocardial contractility and without severe concomitant diseases undergoing myocardial revascularization under artificial circulation. It is ascertained that plasma level of peroxide on the first day after operation is an independent prognostic factor for prolonged hospitalization.

Original languageEnglish (US)
Pages (from-to)49-54
Number of pages6
JournalKardiologiya i Serdechno-Sosudistaya Khirurgiya
Volume6
Issue number4
StatePublished - 2013

All Science Journal Classification (ASJC) codes

  • Surgery
  • Cardiology and Cardiovascular Medicine

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