TY - JOUR
T1 - Impact of intraoperative ischemia time on acute complications of head and neck microvascular free tissue transfer
T2 - A systematic review and meta-analysis
AU - Politano, Stephen F.
AU - Balchander, Divya
AU - Cabrera, Claudia I.
AU - Thuener, Jason E.
AU - Teknos, Theodoros N.
AU - Rezaee, Rod P.
AU - Li, Shawn
AU - Fowler, Nicole
AU - Tamaki, Akina
N1 - Publisher Copyright:
© 2022
PY - 2022/5/1
Y1 - 2022/5/1
N2 - Background: To evaluate the relationship between intraoperative ischemia time with acute microvascular free tissue transfer (MFTT) complications in head and neck reconstruction. Methods: A systematic review using PRISMA guidelines was performed. Inclusion encompassed all available studies published and indexed using PubMed, Medline, and Embase. Meta-analyses were performed using the Cochrane Review Manager tool. Methodological Index for Non-Randomized Studies (MINORS), the Revised Cochrane risk-of-bias tool for randomized trials, and the NIH Study Quality Assessment Tool for non-randomized prospective studies. Results: A total of 430 citations were reviewed. 25 were included in our overall qualitative analysis, and 14 for meta-analysis. When comparing ischemia times for flaps with and without complications, no significant difference was observed (p = 0.98). Additionally, in a separate cohort, no significant effect was realized when correlating ischemia time to overall rates and total complications. Conclusion: Ischemia time was not significantly different between those with and without acute flap complications.
AB - Background: To evaluate the relationship between intraoperative ischemia time with acute microvascular free tissue transfer (MFTT) complications in head and neck reconstruction. Methods: A systematic review using PRISMA guidelines was performed. Inclusion encompassed all available studies published and indexed using PubMed, Medline, and Embase. Meta-analyses were performed using the Cochrane Review Manager tool. Methodological Index for Non-Randomized Studies (MINORS), the Revised Cochrane risk-of-bias tool for randomized trials, and the NIH Study Quality Assessment Tool for non-randomized prospective studies. Results: A total of 430 citations were reviewed. 25 were included in our overall qualitative analysis, and 14 for meta-analysis. When comparing ischemia times for flaps with and without complications, no significant difference was observed (p = 0.98). Additionally, in a separate cohort, no significant effect was realized when correlating ischemia time to overall rates and total complications. Conclusion: Ischemia time was not significantly different between those with and without acute flap complications.
UR - https://www.scopus.com/pages/publications/85127970593
UR - https://www.scopus.com/inward/citedby.url?scp=85127970593&partnerID=8YFLogxK
U2 - 10.1016/j.amjoto.2022.103467
DO - 10.1016/j.amjoto.2022.103467
M3 - Review article
C2 - 35429849
AN - SCOPUS:85127970593
SN - 0196-0709
VL - 43
JO - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
JF - American Journal of Otolaryngology - Head and Neck Medicine and Surgery
IS - 3
M1 - 103467
ER -