TY - JOUR
T1 - Impact of stem cell source and conditioning regimen on erythrocyte recovery kinetics after allogeneic haematopoietic stem cell transplantation from an ABO-incompatible donor
AU - Kanda, Yoshinobu
AU - Tanosaki, Ryuji
AU - Nakai, Kunihisa
AU - Saito, Takeshi
AU - Ohnishi, Mutsuko
AU - Niiya, Hironari
AU - Chizuka, Aki
AU - Yakushijin, Kimikazu
AU - Urahama, Norinaga
AU - Ueda, Kyoji
AU - Iijima, Kimiko
AU - Ando, Toshihiko
AU - Matsubara, Hiroshi
AU - Kami, Masahiro
AU - Makimoto, Atsushi
AU - Kobayashi, Yukio
AU - Tobinai, Kensei
AU - Mineishi, Shin
AU - Takaue, Yoichi
PY - 2002
Y1 - 2002
N2 - We evaluated erythrocyte recovery in 121 allogeneic haematopoietic stem cell transplantation (HSCT) recipients. There were 35 major and minor ABO-incompatible transplants, respectively, including 10 bi-directionally ABO-incompatible transplants. The use of peripheral blood stem cells facilitated erythrocyte recovery, regardless of the presence or absence of major ABO-incompatibility, and was associated with a frequent detection of anti-host isohaemagglutin early after minor ABO-incompatible transplantation, which was not associated with clinically relevant haemolysis. The use of a reduced-intensity regimen combining a purine analogue and busulphan did not delay erythrocyte recovery after major ABO-incompatible transplantation, suggesting this regimen had a strong activity against host plasma cell.
AB - We evaluated erythrocyte recovery in 121 allogeneic haematopoietic stem cell transplantation (HSCT) recipients. There were 35 major and minor ABO-incompatible transplants, respectively, including 10 bi-directionally ABO-incompatible transplants. The use of peripheral blood stem cells facilitated erythrocyte recovery, regardless of the presence or absence of major ABO-incompatibility, and was associated with a frequent detection of anti-host isohaemagglutin early after minor ABO-incompatible transplantation, which was not associated with clinically relevant haemolysis. The use of a reduced-intensity regimen combining a purine analogue and busulphan did not delay erythrocyte recovery after major ABO-incompatible transplantation, suggesting this regimen had a strong activity against host plasma cell.
UR - https://www.scopus.com/pages/publications/0036068283
UR - https://www.scopus.com/pages/publications/0036068283#tab=citedBy
U2 - 10.1046/j.1365-2141.2002.03693.x
DO - 10.1046/j.1365-2141.2002.03693.x
M3 - Article
C2 - 12100136
AN - SCOPUS:0036068283
SN - 0007-1048
VL - 118
SP - 128
EP - 131
JO - British Journal of Haematology
JF - British Journal of Haematology
IS - 1
ER -