Impact of substance use disorders on critical care management and health outcomes in septic adolescents

Havell Markus; Gary D. Ceneviva; Neal J. Thomas; Conrad Krawiec

doi:10.1186/s13613-025-01482-8

Impact of substance use disorders on critical care management and health outcomes in septic adolescents

Research output: Contribution to journal › Article › peer-review

Abstract

Background: Adult septic patients with substance abuse disorder (SUD) are at increased risk of poor outcomes, but the impact on adolescents is unknown. We aimed to determine if pre-existing SUD is associated with increased adverse outcomes and critical care resources in critically ill adolescents hospitalized with sepsis. We hypothesize that SUD is associated with increased risk of adverse outcomes and usage of critical care resources in this adolescent patient population.

Original language	English (US)
Article number	63
Journal	Annals of Intensive Care
Volume	15
Issue number	1
DOIs	https://doi.org/10.1186/s13613-025-01482-8
State	Published - Dec 2025

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Critical Care and Intensive Care Medicine

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10.1186/s13613-025-01482-8

Cite this

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abstract = "Background: Adult septic patients with substance abuse disorder (SUD) are at increased risk of poor outcomes, but the impact on adolescents is unknown. We aimed to determine if pre-existing SUD is associated with increased adverse outcomes and critical care resources in critically ill adolescents hospitalized with sepsis. We hypothesize that SUD is associated with increased risk of adverse outcomes and usage of critical care resources in this adolescent patient population.",

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AU - Markus, Havell

AU - Ceneviva, Gary D.

AU - Thomas, Neal J.

AU - Krawiec, Conrad

N1 - Publisher Copyright: © The Author(s) 2025.

PY - 2025/12

Y1 - 2025/12

N2 - Background: Adult septic patients with substance abuse disorder (SUD) are at increased risk of poor outcomes, but the impact on adolescents is unknown. We aimed to determine if pre-existing SUD is associated with increased adverse outcomes and critical care resources in critically ill adolescents hospitalized with sepsis. We hypothesize that SUD is associated with increased risk of adverse outcomes and usage of critical care resources in this adolescent patient population.

AB - Background: Adult septic patients with substance abuse disorder (SUD) are at increased risk of poor outcomes, but the impact on adolescents is unknown. We aimed to determine if pre-existing SUD is associated with increased adverse outcomes and critical care resources in critically ill adolescents hospitalized with sepsis. We hypothesize that SUD is associated with increased risk of adverse outcomes and usage of critical care resources in this adolescent patient population.

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Impact of substance use disorders on critical care management and health outcomes in septic adolescents

Abstract

UN SDGs

All Science Journal Classification (ASJC) codes

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