Impaired lipogenesis in mammary glands of lactating rats fed on a cafeteria diet. Reversal of inhibition of glucose metabolism in vitro by insulin

L. Agius; B. J. Rolls; E. A. Rowe; D. H. Williamson

doi:10.1042/bj1861005

Impaired lipogenesis in mammary glands of lactating rats fed on a cafeteria diet. Reversal of inhibition of glucose metabolism in vitro by insulin

L. Agius, B. J. Rolls, E. A. Rowe, D. H. Williamson

Nutritional Sciences

Research output: Contribution to journal › Article › peer-review

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Abstract

In lactating rats fed on a cafeteria diet (chow plus palatable high-energy foods) the decreased glucose uptake and lipogenesis in vitro in acini correlated with the depressed mammary-gland lipogenesis in vivo. Insulin in vitro restored the rate of glucose uptake and its conversion to lipid to values approaching those for acini from rats fed on the chow diet alone.

Original language	English (US)
Pages (from-to)	1005-1008
Number of pages	4
Journal	Biochemical Journal
Volume	186
Issue number	3
DOIs	https://doi.org/10.1042/bj1861005
State	Published - 1980

All Science Journal Classification (ASJC) codes

Biochemistry
Molecular Biology
Cell Biology

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10.1042/bj1861005

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abstract = "In lactating rats fed on a cafeteria diet (chow plus palatable high-energy foods) the decreased glucose uptake and lipogenesis in vitro in acini correlated with the depressed mammary-gland lipogenesis in vivo. Insulin in vitro restored the rate of glucose uptake and its conversion to lipid to values approaching those for acini from rats fed on the chow diet alone.",

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AU - Williamson, D. H.

PY - 1980

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Impaired lipogenesis in mammary glands of lactating rats fed on a cafeteria diet. Reversal of inhibition of glucose metabolism in vitro by insulin

Abstract

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