TY - JOUR
T1 - IMPROVE, a community-based exercise intervention versus support group to improve functional and health outcomes among older African American and Non-Hispanic White breast cancer survivors from diverse socioeconomic backgrounds
T2 - Recruitment strategies and baseline characteristics
AU - Owusu, Cynthia
AU - Nock, Nora L.
AU - Feuntes, Vanessa
AU - Margevicius, Seunghee
AU - Hergenroeder, Paul
AU - Austin, Kristina
AU - Bennet, Elizabeth
AU - Cerne, Stephen
AU - Moore, Halle C.F.
AU - Petkac, Jean
AU - Schluchter, Mark
AU - Schmitz, Kathryn H.
AU - Webb Hooper, Monica
AU - Coccia, Sarah
AU - Nagy, Caitlin
AU - Wimbley, Leonard
AU - Berger, Nathan A.
N1 - Funding Information:
Halle C. F. Moore reports grants from National Institutes of Health during the conduct of the study; and institutional research support from AstraZeneca, Roche/Genentech, Daiichi‐Sankyo, AbbVie, Sermonix, and PUMA outside the submitted work. The remaining authors made no disclosures.
Funding Information:
This work was supported by the National Institute on Minority Health and Health Disparities (grant R01 MD009699 to Cynthia Owusu).
Publisher Copyright:
© 2021 American Cancer Society
PY - 2021/6/1
Y1 - 2021/6/1
N2 - Background: Behavioral intervention studies in older breast cancer survivors, particularly older African American (AA) and socioeconomic status–disadvantaged breast cancer survivors, are lacking. To inform future studies, the authors examined recruitment strategies in older breast cancer survivors who participated in an exercise intervention study. Methods: IMPROVE is a randomized trial designed to evaluate a group-based exercise intervention versus a support group (ClinicalTrials.gov identifier, NCT02763228). Participants were aged ≥65 years who had survived stage I through III breast cancer and were within 5 years of treatment completion. Participants were recruited through multiple approaches, including peripheral, linguistic, and constituent-involving strategies that incorporated the identification of potentially eligible patients from 3 local hospitals and from State of Ohio registries and through direct clinician and community organization referrals. Results: Between October 2016 and November 2019, 7487 patients were screened, 4790 were potentially eligible, and 213 were randomized into the study. The eligible:randomization rates were 4.4% overall and 84%, 8%, and 2% for recruitment using direct referrals, hospital registries, and state registries, respectively. The median age of the randomized cohort was 70 years (range, 65-88 years) and included 44% AA and 44% socioeconomic status–disadvantaged breast cancer survivors. Compared with all registry-eligible patients, directly referred-eligible patients were more likely to be AA versus Non-Hispanic White (41% vs 19%; P =.006), to be contacted successfully (100% vs 33%; P <.0001), and to accept study participation (88% vs 16%; P <.0001). Conclusions: Direct referrals appeared to be the most efficient strategy for recruiting AA survivors. Behavioral intervention studies seeking to target older AA and socioeconomic status–disadvantaged breast cancer survivors should include strategies that foster direct referrals to study participation.
AB - Background: Behavioral intervention studies in older breast cancer survivors, particularly older African American (AA) and socioeconomic status–disadvantaged breast cancer survivors, are lacking. To inform future studies, the authors examined recruitment strategies in older breast cancer survivors who participated in an exercise intervention study. Methods: IMPROVE is a randomized trial designed to evaluate a group-based exercise intervention versus a support group (ClinicalTrials.gov identifier, NCT02763228). Participants were aged ≥65 years who had survived stage I through III breast cancer and were within 5 years of treatment completion. Participants were recruited through multiple approaches, including peripheral, linguistic, and constituent-involving strategies that incorporated the identification of potentially eligible patients from 3 local hospitals and from State of Ohio registries and through direct clinician and community organization referrals. Results: Between October 2016 and November 2019, 7487 patients were screened, 4790 were potentially eligible, and 213 were randomized into the study. The eligible:randomization rates were 4.4% overall and 84%, 8%, and 2% for recruitment using direct referrals, hospital registries, and state registries, respectively. The median age of the randomized cohort was 70 years (range, 65-88 years) and included 44% AA and 44% socioeconomic status–disadvantaged breast cancer survivors. Compared with all registry-eligible patients, directly referred-eligible patients were more likely to be AA versus Non-Hispanic White (41% vs 19%; P =.006), to be contacted successfully (100% vs 33%; P <.0001), and to accept study participation (88% vs 16%; P <.0001). Conclusions: Direct referrals appeared to be the most efficient strategy for recruiting AA survivors. Behavioral intervention studies seeking to target older AA and socioeconomic status–disadvantaged breast cancer survivors should include strategies that foster direct referrals to study participation.
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U2 - 10.1002/cncr.33430
DO - 10.1002/cncr.33430
M3 - Article
C2 - 33539554
AN - SCOPUS:85100336819
SN - 0008-543X
VL - 127
SP - 1836
EP - 1846
JO - Cancer
JF - Cancer
IS - 11
ER -