Improved Annotation of Untargeted Metabolomics Data through Buffer Modifications That Shift Adduct Mass and Intensity

Keyphrases

• Liquid Chromatography-tandem Mass Spectrometry (LC-MS/MS) 100%
• Untargeted Metabolomics 100%
• Metabolomics Data 100%
• Isotopic Labeling 66%
• High-resolution 33%
• Chromatography 33%
• Liquid Chromatography 33%
• Biological Samples 33%
• Tumor 33%
• Liver 33%
• Formate 33%
• Mouse Liver 33%
• Adduct Formation 33%
• Mammalian Tissue 33%
• Biological Species 33%
• Mass Difference 33%
• KEGG Database 33%
• Untargeted 33%
• Full-scan 33%
• Signal Intensity Change 33%

Chemistry

• Buffer Solution 100%
• Liquid Chromatography Mass Spectrometry 80%
• Metabolite 60%
• Formate 20%
• Liquid Chromatography 20%
• formation 20%

Pharmacology, Toxicology and Pharmaceutical Science

• Buffer 100%
• Neoplasm 20%
• Formate 20%