In-Cell Penetration Selection-Mass Spectrometry Produces Noncanonical Peptides for Antisense Delivery

Keyphrases

• Mass Spectrometry 100%
• Macromolecules 100%
• Cargo 100%
• Endosome 100%
• Cell Penetration 100%
• Cell-penetrating Peptide 100%
• Phosphorodiamidate Morpholino Oligomers 100%
• Amino Acids 50%
• Microscopy 50%
• Selection Strategy 50%
• Subcellular Fractionation 50%
• Spatial Dimension 50%
• Potential Therapeutics 50%
• Cell Surface 50%
• Antisense 50%
• Whole Cell Extract 50%
• Endosomal 50%
• Less Toxic 50%
• Cytoplasmic Extract 50%
• Synthetic Peptides 50%
• Unnatural 50%
• Therapeutic Implications 50%
• Pulse-chase 50%
• In Vivo Selection 50%
• Synthetic Library 50%
• Cytosol 50%

Chemistry

• Mass Spectrometry 100%
• Antisense 100%
• Peptide 100%
• Macromolecule 40%
• Cell-Penetrating Peptide 40%
• Oligomer 40%
• Fractionation 20%
• Toxic 20%
• Amino Acid 20%