In vitro activity of CI-934, a new quinolone antimicrobial, against gram-positive bacteria

G. M. Eliopoulos; E. Reiszner; Gregory Caputo; R. C. Moellering

doi:10.1016/0732-8893(86)90040-4

In vitro activity of CI-934, a new quinolone antimicrobial, against gram-positive bacteria

G. M. Eliopoulos
, E. Reiszner
, Gregory Caputo
, R. C. Moellering

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

The in vitro activity of CI-934, a new quinolone antimicrobial, was compared with that of ciprofloxacin against selected gram-positive bacteria. Concentrations of CI-934 required to inhibit 90% of strains (MIC₉₀) were twofold to eightfold lower than those of ciprofloxacin. With the exception of Streptococcus faecium, all isolates were inhibited by CI-934 at concentrations ≤1.0 μg/ml.

Original language	English (US)
Pages (from-to)	341-344
Number of pages	4
Journal	Diagnostic Microbiology and Infectious Disease
Volume	5
Issue number	4
DOIs	https://doi.org/10.1016/0732-8893(86)90040-4
State	Published - Nov 1986

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This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

All Science Journal Classification (ASJC) codes

Microbiology (medical)
Infectious Diseases

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10.1016/0732-8893(86)90040-4

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abstract = "The in vitro activity of CI-934, a new quinolone antimicrobial, was compared with that of ciprofloxacin against selected gram-positive bacteria. Concentrations of CI-934 required to inhibit 90\% of strains (MIC90) were twofold to eightfold lower than those of ciprofloxacin. With the exception of Streptococcus faecium, all isolates were inhibited by CI-934 at concentrations ≤1.0 μg/ml.",

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AU - Caputo, Gregory

AU - Moellering, R. C.

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AB - The in vitro activity of CI-934, a new quinolone antimicrobial, was compared with that of ciprofloxacin against selected gram-positive bacteria. Concentrations of CI-934 required to inhibit 90% of strains (MIC90) were twofold to eightfold lower than those of ciprofloxacin. With the exception of Streptococcus faecium, all isolates were inhibited by CI-934 at concentrations ≤1.0 μg/ml.

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ER -

In vitro activity of CI-934, a new quinolone antimicrobial, against gram-positive bacteria

Abstract

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