In vitro loss of heterozygosity targets the PTEN/MMAC1 gene in melanoma

Keyphrases

• Melanoma 100%
• Loss of Heterozygosity 100%
• Tumor Suppressor Gene 66%
• Chromosome 10 66%
• Functional Significance 33%
• Breakage 33%
• Melanoma Cells 33%
• Malignant Melanoma 33%
• Genetic Lesions 33%
• Suppression Effect 33%
• Ectopic Expression 33%
• Human Melanoma 33%
• Alternative Means 33%
• Truncating mutation 33%
• Cell Suppression 33%

Biochemistry, Genetics and Molecular Biology

• Loss of Heterozygosity 100%
• Wild Type 66%
• Tumor Suppressor Gene 66%
• Chromosome 10 66%
• Allele 33%
• Genetics 33%
• Growth Inhibition 33%
• Cell Growth 33%
• Ectopic Expression 33%