TY - JOUR
T1 - In vivo versus in vitro polymerization of acrylic bone cement
T2 - Effect on material properties
AU - Bargar, W. L.
AU - Brown, S. A.
AU - Paul, H. A.
AU - Voegli, T.
AU - Hseih, Y.
AU - Sharkey, N.
PY - 1986
Y1 - 1986
N2 - Flexural strength and molecular weight of polymethylmethacrylate bone cement were determined for cement polymerized in vivo in a canine total hip replacement and cement from the same batch polymerized in vitro. Both in vivo and in vitro samples showed a slight increase in flexural strength and modulus at 2 weeks, followed by a nearly equivalent decline at 8 weeks. In vitro and in vivo samples exhibit a comparable stress to failure, but the in vivo samples show a significantly increased strain and decreased modulus. Cement from the proximal region of the prosthesis has significantly decreased flexural strength, lower modulus, and lower molecular weight than cement from the distal region and plug, suggesting that failures in the proximal region of a prosthesis may be due to inferior physical and mechanical properties of the bone cement in that region.
AB - Flexural strength and molecular weight of polymethylmethacrylate bone cement were determined for cement polymerized in vivo in a canine total hip replacement and cement from the same batch polymerized in vitro. Both in vivo and in vitro samples showed a slight increase in flexural strength and modulus at 2 weeks, followed by a nearly equivalent decline at 8 weeks. In vitro and in vivo samples exhibit a comparable stress to failure, but the in vivo samples show a significantly increased strain and decreased modulus. Cement from the proximal region of the prosthesis has significantly decreased flexural strength, lower modulus, and lower molecular weight than cement from the distal region and plug, suggesting that failures in the proximal region of a prosthesis may be due to inferior physical and mechanical properties of the bone cement in that region.
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U2 - 10.1002/jor.1100040110
DO - 10.1002/jor.1100040110
M3 - Article
C2 - 3950811
AN - SCOPUS:0022590581
SN - 0736-0266
VL - 4
SP - 86
EP - 89
JO - Journal of Orthopaedic Research
JF - Journal of Orthopaedic Research
IS - 1
ER -