Increased fibrinogen level increases leukocyte-endothelial cell adhesion

Mark Pearson, Herbert Lipowsky

Research output: Contribution to journalConference articlepeer-review


The relative role of RCA and WBC adhesion, fibrinogen was infused into the circulation and WBC margination and adhesion measured at various shear rates in mesentric venules of rat. WBC margination was measured as the percentage of total WBC volume flux at the venular wall (FWBC). Results suggest that fibrinogen is an important determinant of WBC-EC adhesion.

Original languageEnglish (US)
Pages (from-to)S-76
JournalAnnals of Biomedical Engineering
Issue numberSUPPL. 1
StatePublished - 2000
Event2000 Annual Fall Meeting of the Biomedical Engineering Society - Washington, WA, USA
Duration: Oct 12 2000Oct 14 2000

All Science Journal Classification (ASJC) codes

  • Biomedical Engineering


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