TY - JOUR
T1 - Individuals with spinal cord injury have greater odds of substance use disorders than non-sci comparisons
AU - Graupensperger, Scott
AU - Corey, Jacob J.
AU - Turrisi, Robert J.
AU - Evans, Michael B.
N1 - Funding Information:
As described in section 4.2, this study was funded by the NIH National Center for Advancing Translational Sciences ( TL1 TR002016 ) and National Institute for Drug Abuse ( T32 DA017629 ). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The funding sources played no role in study design; collection, analysis and interpretation of data; in writing the report; or in the decision to submit the article for publication.
Funding Information:
The project described was supported by the NIH National Center for Advancing Translational Sciences (TL1 TR002016) and National Institute for Drug Abuse (T32 DA017629). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The funding sources played no role in study design; collection, analysis and interpretation of data; in writing the report; or in the decision to submit the article for publication.
Funding Information:
As described in section 4.2, this study was funded by the NIH National Center for Advancing Translational Sciences (TL1 TR002016) and National Institute for Drug Abuse (T32 DA017629). The content is solely the responsibility of the authors and does not necessarily represent the official views of the NIH. The funding sources played no role in study design; collection, analysis and interpretation of data; in writing the report; or in the decision to submit the article for publication.
Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2019/12/1
Y1 - 2019/12/1
N2 - Background: Individuals with spinal cord injury (SCI) are disproportionately affected by numerous physical and behavioral health disparities, but the literature lacks a clear understanding of the association between SCI and substance use disorders. Identifying such behavioral health disparities in persons with disabilities is an increasingly central focus for public health researchers and represents a critical first step for prevention. Method: The present study utilized a large database of deidentified electronic health records to examine the association between SCI and substance use disorders related to alcohol, cannabis, opioid, and nicotine. Examining data from patients 16 years or older who had patient encounters at the Penn State Hershey Medical Center from January 1, 1997 to April 30, 2018, the current study included data from 1,466,985 unique patients – 6192 of which held SCI diagnoses. Age-adjusted odds ratios were calculated using logistic regression. Results: Compared to non-SCI patients, individuals with SCI were at increased odds of having alcohol use disorder (OR: 4.19, 95% CI [3.67, 4.80]), cannabis use disorder (OR: 7.83, 95% CI [6.32, 9.69]), opioid use disorder (OR: 7.97, 95% CI [6.59, 9.66]), and nicotine use disorder (OR: 4.66, 95% CI [4.40, 4.94]). Patient sex did not moderate any of the four associations. Conclusion: This study provides early indication that individuals with SCI may be disproportionately at-risk for substance use disorders and provides a foundation for future mechanistic and translational research. This evidence is a valuable step towards improving the health and quality of life for individuals with SCI.
AB - Background: Individuals with spinal cord injury (SCI) are disproportionately affected by numerous physical and behavioral health disparities, but the literature lacks a clear understanding of the association between SCI and substance use disorders. Identifying such behavioral health disparities in persons with disabilities is an increasingly central focus for public health researchers and represents a critical first step for prevention. Method: The present study utilized a large database of deidentified electronic health records to examine the association between SCI and substance use disorders related to alcohol, cannabis, opioid, and nicotine. Examining data from patients 16 years or older who had patient encounters at the Penn State Hershey Medical Center from January 1, 1997 to April 30, 2018, the current study included data from 1,466,985 unique patients – 6192 of which held SCI diagnoses. Age-adjusted odds ratios were calculated using logistic regression. Results: Compared to non-SCI patients, individuals with SCI were at increased odds of having alcohol use disorder (OR: 4.19, 95% CI [3.67, 4.80]), cannabis use disorder (OR: 7.83, 95% CI [6.32, 9.69]), opioid use disorder (OR: 7.97, 95% CI [6.59, 9.66]), and nicotine use disorder (OR: 4.66, 95% CI [4.40, 4.94]). Patient sex did not moderate any of the four associations. Conclusion: This study provides early indication that individuals with SCI may be disproportionately at-risk for substance use disorders and provides a foundation for future mechanistic and translational research. This evidence is a valuable step towards improving the health and quality of life for individuals with SCI.
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U2 - 10.1016/j.drugalcdep.2019.107608
DO - 10.1016/j.drugalcdep.2019.107608
M3 - Article
C2 - 31606588
AN - SCOPUS:85072963966
SN - 0376-8716
VL - 205
JO - Drug and alcohol dependence
JF - Drug and alcohol dependence
M1 - 107608
ER -
