TY - JOUR
T1 - Induction of labor compared to expectant management in low-risk women and associated perinatal outcomes
AU - Cheng, Yvonne W.
AU - Kaimal, Anjali J.
AU - Snowden, Jonathan M.
AU - Nicholson, James M.
AU - Caughey, Aaron B.
N1 - Funding Information:
Y.W.C. is supported by the University of California San Francisco Women's Reproductive Health Research Career Development Award, National Institutes of Health, the Eunice Kennedy Shriver National Institute of Child Health and Human Development ( K12 HD001262 ).
PY - 2012/12
Y1 - 2012/12
N2 - Objective: We sought to examine the association of labor induction and perinatal outcomes. Study Design: This was a retrospective cohort study of low-risk nulliparous women with term, live births. Women who had induction at a given gestational age (eg, 39 weeks) were compared to delivery at a later gestation (eg, 40, 41, or 42 weeks). Results: Compared to delivery at a later gestational age, those induced at 39 weeks had a lower risk of cesarean (adjusted odds ratio [aOR], 0.90; 95% confidence interval [CI], 0.88-0.91) and labor dystocia (aOR, 0.88; 95% CI, 0.84-0.94). Their neonates had lowered risk of having 5-minute Apgar <7 (aOR, 0.81; 95% CI, 0.72-0.92), meconium aspiration syndrome (aOR, 0.30; 95% CI, 0.19-0.48), and admission to neonatal intensive care unit (aOR, 0.87; 95% CI, 0.78-0.97). Similar findings were seen for women who were induced at 40 weeks compared to delivery later. Conclusion: Induction of labor in low-risk women at term is not associated with increased risk of cesarean delivery compared to delivery later.
AB - Objective: We sought to examine the association of labor induction and perinatal outcomes. Study Design: This was a retrospective cohort study of low-risk nulliparous women with term, live births. Women who had induction at a given gestational age (eg, 39 weeks) were compared to delivery at a later gestation (eg, 40, 41, or 42 weeks). Results: Compared to delivery at a later gestational age, those induced at 39 weeks had a lower risk of cesarean (adjusted odds ratio [aOR], 0.90; 95% confidence interval [CI], 0.88-0.91) and labor dystocia (aOR, 0.88; 95% CI, 0.84-0.94). Their neonates had lowered risk of having 5-minute Apgar <7 (aOR, 0.81; 95% CI, 0.72-0.92), meconium aspiration syndrome (aOR, 0.30; 95% CI, 0.19-0.48), and admission to neonatal intensive care unit (aOR, 0.87; 95% CI, 0.78-0.97). Similar findings were seen for women who were induced at 40 weeks compared to delivery later. Conclusion: Induction of labor in low-risk women at term is not associated with increased risk of cesarean delivery compared to delivery later.
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U2 - 10.1016/j.ajog.2012.09.019
DO - 10.1016/j.ajog.2012.09.019
M3 - Article
C2 - 23063017
AN - SCOPUS:84869502862
SN - 0002-9378
VL - 207
SP - 502.e1-502.e8
JO - American journal of obstetrics and gynecology
JF - American journal of obstetrics and gynecology
IS - 6
ER -