TY - JOUR
T1 - Induction of ornithine decarboxylase in colon and liver by starvation and refeeding
T2 - A comparison of effects on total and holoenzyme
AU - Stanley, Bruce A.
AU - Kazarinoff, Michael N.
PY - 1982/3/30
Y1 - 1982/3/30
N2 - In rats, short-term starvation and subsequent refecding induced both holo- and total ornithine decarboxylase (EC 4.1.1.17) levels in colon 5-fold over ad lib fed controls. Starvation alone led to a significant decrease in total ornithine decarboxylase level in colon, while no change was seen in the holoenzyme level. There are only two reported short-term chemical inducers of colon ornithine decarboxylase, and this is the first demonstration of dietary induction in this tissue. Liver total ornithine decarboxylase was also induced by starvation-refeeding, but no holoenzyme effects were seen in any treatment.
AB - In rats, short-term starvation and subsequent refecding induced both holo- and total ornithine decarboxylase (EC 4.1.1.17) levels in colon 5-fold over ad lib fed controls. Starvation alone led to a significant decrease in total ornithine decarboxylase level in colon, while no change was seen in the holoenzyme level. There are only two reported short-term chemical inducers of colon ornithine decarboxylase, and this is the first demonstration of dietary induction in this tissue. Liver total ornithine decarboxylase was also induced by starvation-refeeding, but no holoenzyme effects were seen in any treatment.
UR - http://www.scopus.com/inward/record.url?scp=0020464110&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=0020464110&partnerID=8YFLogxK
U2 - 10.1016/0006-291X(82)91501-7
DO - 10.1016/0006-291X(82)91501-7
M3 - Article
C2 - 7092886
AN - SCOPUS:0020464110
SN - 0006-291X
VL - 105
SP - 773
EP - 777
JO - Biochemical and Biophysical Research Communications
JF - Biochemical and Biophysical Research Communications
IS - 2
ER -