Influence of age and gender on cardiac output-V̇o2 relationships during submaximal cycle ergometry

David N. Proctor, Kenneth C. Beck, Peter H. Shen, Tamara J. Eickhoff, John R. Halliwill, Michael J. Joyner

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102 Scopus citations


It is presently unclear how gender aging physical activity status interact to determine the magnitude of the rise in cardiac output (Qc) during dynamic exercise. To clarify this issue the present study examined the Qc- O2 uptake (V̇(O2) relationship during graded leg cycle ergometry in 30 chronically endurance-trained subjects from four groups (n = 6-8/group): younger men (20-30 yr) older men (56-7.2 yr) younger women (24-31 yr) older women (51-72 yr). Qc (acetylene rebreathing) stroke volume (Qc/heart rate) whole body V̇(O2) were measured at rest during submaximal exercise intensities (40, 70, and ~90% of peak V̇(O2)). Baseline resting levels of Qc were 0.6-1.2 l/min less in the older groups. However, the slopes of the Qc-V̇(O2) relationship across submaximal levels of cycling were similar among all four groups (5.4-5.9 l/l). The absolute Qc associated with a given V̇(O2) (1.0-2.0 l/min) was also similar among groups. Resting and exercise stroke volumes (ml/beat) were lower in women than in men but did not differ among age groups. However, older men and women showed a reduced ability, relative to their younger counterparts, to maintain stroke volume at exercise intensifies above 70% of peak V̇(O2). This latter effect was most prominent in the oldest women. These findings suggest that neither age nor gender has a significant impact on the Qc-V̇(O2) relationships during submaximal cycle ergometry among chronically endurance-trained individuals.

Original languageEnglish (US)
Pages (from-to)599-605
Number of pages7
JournalJournal of applied physiology
Issue number2
StatePublished - Feb 1998

All Science Journal Classification (ASJC) codes

  • Physiology
  • Physiology (medical)


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