TY - JOUR
T1 - Influence of treatment for disruptive behavior disorders on adrenal and gonadal hormones in youth
AU - Dorn, Lorah D.
AU - Kolko, David J.
AU - Shenk, Chad E.
AU - Susman, Elizabeth J.
AU - Bukstein, Oscar
PY - 2011/7
Y1 - 2011/7
N2 - The study examined whether psychosocial intervention for children diagnosed with a disruptive behavior disorder (DBD; n=84) changed concentrations of cortisol and testosterone across a 3-year follow-up when compared to a matched, nonclinical, healthy comparison (HC; n=69) group. Boys and girls (6-11 years) with a DBD were randomly assigned to one of two arms of a multimethod intervention. Hierarchical linear modeling revealed that children undergoing psychosocial intervention for a DBD experienced a significant decline in diurnal cortisol change over time (p<.05) when compared to the HC condition. Boys with a DBD diagnosis had significantly lower mean cortisol concentrations prior to treatment (p<.05) and showed a significantly steeper increase in mean cortisol over time (p<.05) when compared to HC boys. Treatment effects for diurnal cortisol change were replicated in the boys-only analysis. No treatment effects were noted for testosterone in either analysis.
AB - The study examined whether psychosocial intervention for children diagnosed with a disruptive behavior disorder (DBD; n=84) changed concentrations of cortisol and testosterone across a 3-year follow-up when compared to a matched, nonclinical, healthy comparison (HC; n=69) group. Boys and girls (6-11 years) with a DBD were randomly assigned to one of two arms of a multimethod intervention. Hierarchical linear modeling revealed that children undergoing psychosocial intervention for a DBD experienced a significant decline in diurnal cortisol change over time (p<.05) when compared to the HC condition. Boys with a DBD diagnosis had significantly lower mean cortisol concentrations prior to treatment (p<.05) and showed a significantly steeper increase in mean cortisol over time (p<.05) when compared to HC boys. Treatment effects for diurnal cortisol change were replicated in the boys-only analysis. No treatment effects were noted for testosterone in either analysis.
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U2 - 10.1080/15374416.2011.581614
DO - 10.1080/15374416.2011.581614
M3 - Article
C2 - 21722028
AN - SCOPUS:79960496505
SN - 1537-4416
VL - 40
SP - 562
EP - 571
JO - Journal of Clinical Child and Adolescent Psychology
JF - Journal of Clinical Child and Adolescent Psychology
IS - 4
ER -