Informing a sinusitis clinical trial protocol: A focus group study with clinicians and staff

Ruey Ying Liu; Charles Fencil; Tom Whitfield; Daniel Merenstein; Bruce Barrett; David Rabago; Alex H. Krist; Sebastian T. Tong; Aleksandra E. Zgierska; Derjung M. Tarn

doi:10.1017/cts.2024.663

Informing a sinusitis clinical trial protocol: A focus group study with clinicians and staff

Ruey Ying Liu, Charles Fencil, Tom Whitfield, Daniel Merenstein, Bruce Barrett, David Rabago, Alex H. Krist, Sebastian T. Tong, Aleksandra E. Zgierska, Derjung M. Tarn

Research output: Contribution to journal › Article › peer-review

Abstract

This study investigates practicing clinician and staff perspectives on potential protocol modifications for the Nasal Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis (NOSES) study, a pragmatic randomized controlled trial aiming at improving acute rhinosinusitis management. Focus groups with clinicians and staff at the pretrial stage recommended expanding participant age inclusion criteria, incorporating patients with COVID-19, and shortening the supportive care phase. Participants also discussed patient engagement and recruitment strategies. These practical insights contribute to optimizing the NOSES trial design and underscore the value of qualitative inquiries and healthcare stakeholder engagement in informing clinical trial design.

Original language	English (US)
Article number	e225
Journal	Journal of Clinical and Translational Science
Volume	8
Issue number	1
DOIs	https://doi.org/10.1017/cts.2024.663
State	Published - Nov 27 2024

All Science Journal Classification (ASJC) codes

General Medicine

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10.1017/cts.2024.663

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abstract = "This study investigates practicing clinician and staff perspectives on potential protocol modifications for the Nasal Irrigation, Oral Antibiotics, and Subgroup Targeting for Effective Management of Acute Sinusitis (NOSES) study, a pragmatic randomized controlled trial aiming at improving acute rhinosinusitis management. Focus groups with clinicians and staff at the pretrial stage recommended expanding participant age inclusion criteria, incorporating patients with COVID-19, and shortening the supportive care phase. Participants also discussed patient engagement and recruitment strategies. These practical insights contribute to optimizing the NOSES trial design and underscore the value of qualitative inquiries and healthcare stakeholder engagement in informing clinical trial design.",

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AU - Barrett, Bruce

AU - Rabago, David

AU - Krist, Alex H.

AU - Tong, Sebastian T.

AU - Zgierska, Aleksandra E.

AU - Tarn, Derjung M.

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Informing a sinusitis clinical trial protocol: A focus group study with clinicians and staff

Abstract

All Science Journal Classification (ASJC) codes

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