Inhibition of cell growth and induction of apoptosis in non-small cell lung cancer cells by delta-tocotrienol is associated with notch-1 down-regulation

Keyphrases

• Notch1 100%
• Cell Growth 100%
• Non-small Cell Lung Cancer Cells 100%
• Apoptosis Induction 100%
• Lung Cancer 40%
• Non-small Cell Lung Cancer (NSCLC) 40%
• NF-B 40%
• Signaling Pathway 20%
• Tumor Progression 20%
• Cell Differentiation 20%
• DNA Binding 20%
• Western Blot Analysis 20%
• Cell Proliferation 20%
• 5-year Survival 20%
• Tumor Cells 20%
• Cell Apoptosis 20%
• Leading Causes of Death 20%
• Non-small Cell Lung Cancer Patients 20%
• Cell Migration 20%
• Vitamin E 20%
• Survivin 20%
• Bcl-xL 20%
• Antitumor Activity 20%
• Notch Signaling 20%
• Antitumor Effect 20%
• Matrix metalloproteinase-9 (MMP-9) 20%
• Cancer Cell Growth 20%
• All Cancer 20%
• Real-time RT-PCR 20%
• Hes1 20%
• Cell Invasiveness 20%
• Notch1 Signaling 20%
• Notch Pathway 20%
• Time-dependent Inhibition 20%

Biochemistry, Genetics and Molecular Biology

• Cancer Cell 100%
• Downregulation 100%
• Cell Growth 100%
• Notch-1 100%
• Programmed Cell Death 100%
• Tocotrienol 100%
• Binding Affinity 16%
• Notch 16%
• DNA Binding 16%
• Survival Rate 16%
• Isoform 16%
• Cell Proliferation 16%
• Western Blot 16%
• Tumor Progression 16%
• Cell Migration 16%
• Survivin 16%
• Gelatinase B 16%
• MMP9 16%
• Notch Signaling Pathway 16%
• Vascular Endothelial Growth Factor 16%
• Cell Invasion 16%
• Antineoplastic Activity 16%
• Quantitative Reverse Transcription Polymerase Chain Reaction 16%
• Vitamin E 16%

Pharmacology, Toxicology and Pharmaceutical Science

• Non Small Cell Lung Cancer 100%
• Alpha Tocotrienol 100%
• Lung Cancer 40%
• Metastasis 20%
• Neoplasm 20%
• Tumor Growth 20%
• Survival Rate 20%
• Cancer Growth 20%
• Vasculotropin 20%
• Western Blot 20%
• Alpha Tocopherol 20%
• Survivin 20%
• Antitumor Activity 20%
• Gelatinase B 20%
• DNA B 20%